Antagonism 1. | Interaction of two substances, e.g. hormones, enzymes, drugs etc. that have opposing effects, resulting in one of the substances being completely inhibited by the effect of the other. e.g. Insulin and glucagon are antagonistic hormones, whereby insulin secreted by beta cells facilitates the elimination of glucose from the blood and store excess glucose as glycogen. Conversely, glucagon secreted by alpha cells facilities the release of glucose from stored glycogen.
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